Vidya Prasarak Mandal's
ADVANCED STUDY CENTRE
C/o. B. N. Bandodkar College of Science, Thane (W).
400601.
E-mail: vpmt@vsnl.net Tel. No.: 022 – 25339871 URL: www.vpmthane.org
SYLLABUS
PAPER – I: Fundamentals of Analytical Chemistry and Legal Aspects (100 marks)
1:
Errors, Precision and Accuracy
1.1 Introduction
1.2 Types of errors
1.3 Precision and
accuracy
1.4 Method of
expressing accuracy
1.5 Methods of
expressing precision
2:
Statistical Quality Control
3:
Calibration
Calibration
of burette, pipette, graduated pipette & standard volumetric flask using
monopan balance
4:
Introduction to Analytical Chemistry & Basic Physio Chemical Principles
4.1 Basic principles, current voltage, curve with polarization, factors affecting the current
voltage curve- residual current, migration current, diffusion current
4.2 Working of polar-graphic unit having dropping mercury electrode, stripping method,
differential pulse polarography
4.3 Applications
5: Potentiometric Titration
& Volumetric Analysis
5.1 Introduction to potentiometric titration
5.2 Instrumentation
5.3 Types of potentiometric titration
5.4 Advantages of potentiometric titration
5.5 Introduction to volumetric analysis
5.6 Acid base titration, Redox titration, Complexometric titration, Aqueous titration
6: Solvent Extraction &
Separation Techniques
6.1 Introduction
6.2 Extraction methods
6.3 Extraction techniques
6.4 Applications
7: Limit Tests
7.1 Specificity and sensitivity of limit test
7.2 Limits of moisture, volatile matter and residual solvents
7.3 Limits of residue on drying
7.4 Limit test for metallic impurities
7.5 Determination of moisture content by Karl Fischer method
8: Introduction to Legal
Aspects
8.1 Sampling in chemical industry
8.2 Quality Assurance (QA)
8.3 Introduction to current Good Manufacturing Practices (GMP)
8.4 Quality Control (QC)
8.5 Good Laboratory Practices GLP
8.6 Introduction to ISO, ISO 9000 and ISO 14000
8.7 Total Quality Management
8.8 Kaizen principles
8.9 Introduction to various Laws related chemical industry
8.10 Introduction to packaging material testing
8.11 Industrial methods of development and validation
PAPER
– II: Instrumental Methods of Chemical Analysis (100 marks)
1: Infrared Absorption Spectroscopy
1.1 Theory of Infrared Absorption Spectroscopy
1.2 Instrumentation (Double beam spectrophotometer)
1.3 Modes of vibration and factors influencing vibrational frequencies
1.4 Sampling techniques
1.5 Position and intensity of bands
1.6 Applications of Infrared Spectroscopy
2: Colorimetry, Ultraviolet and Visible Spectroscopy
2.1 Theory of Colorimetry, Ultraviolet and Visible Spectroscopy
2.2 Instrumentation
2.3 The concept of Auxochrome and Chromophone
2.4 Effect of conjugation and solvent effect
2.5 Woodword-Feiser rules for calculating absorption maxima
2.6 Applications – qualitative and quantitative
3: Nuclear Magnetic Resonance Spectroscopy (NMR)
3.1 Introduction
3.2 Rules predicting spin number of Nuclei and calculation of spin numbers
3.3 Number of signals, Chemical Shift of different types of protons coupling constant (J)
3.4 Spin-spin coupling, Splitting of signals
3.5 Interpretation of NMR spectroscopy
4: Mass Spectrometry
4.1 Theory and basic principles
4.2 Instrumentation
4.3 Metastable ions or peaks
4.4 General fragmentation modes
4.5 Typical examples of interpretation of mass spectra
5: Flame Photometry
5.1 Principles of Flame Photometry
5.2 Instrumentation
5.3 Effect of solvent in Flame Photometry
5.4 Interferences in Flame Photometry
5.5 Limitations and applications of Flame Photometry
6: Atomic Absorption Spectroscopy (AAS)
6.1 Principles and Instrumentation
6.2 Detections of non-metals by AAS
6.3 Difference between Atomic Absorption Spectroscopy & Flame Emission
Spectroscopy
6.4 Detection limit and sensitivity
6.5 Applications and disadvantages of AAS
7: Nephelometry and
Turbidimetry
7.1 Introduction and Instrumentation
7.2 Theory
7.3 Comparison between Nephelometry and Turbidimetry
7.4 Applications
8: Thermal Analytical Methods
8.1 Introduction
8.2 Differential Thermal Analysis (DTA)
8.3 Differential Scanning Colorimetry (DSC)
8.4 Factors affecting thermal methods
9: Gas Chromatography (GC)
9.1 Principles of GC separations
9.2 Instrumentation
9.3 Selection of and various types of columns
9.4 Methods of analysis
9.5 Applications - qualitative and quantitative
9.6 Limitations of GC
10: High Performance Liquid
Chromatography (HPLC)
10.1 Principles of HPLC
10.2 Instrumentation
10.3 Column efficiency and selectivity
10.4 Applications
10.5 Comparison between GC and HPLC
11: Column Chromatography
11.1 Introduction
11.2 Theory and Principles
11.3 Column efficiency
11.4 Applications of column chromatography
PAPER
– III Environment Science and Laboratory Safety
(100 marks)
1: Water
1.1 Sources of water
1.2 Impurities in water
1.3 Requirements of potable / drinking water
2: Technical
(Theoretical) Aspects of Water Analysis
2.1 Estimation of total solid, oil and greases, determination of total alkalinity & sulphate
2.2 Estimation of total hardness
2.3 Estimation of Dissolved Oxygen (DO) by Wrinkler Method
2.4 Estimation of Chemical Oxygen Demand (COD)
2.5 Estimation of Biological Oxygen Demand (BOD)
3: Purification of Water
3.1 Removal of Micro-organism
3.2 Removal of hardness of water
3.3 Lime sods process
3.4 Zeolite
3.5 Ion-exchange, Deionization and De-mineralization process
4: Air
4.1 Composition of air
4.2 Air pollutants
4.3 Impact of air pollution on environment
4.4 Air pollution analysis and monitoring
4.5 Remedial measures
5: Introduction to Soil
Analysis
6: Safety in Laboratory
6.1 Fundamental of Safety
6.2 Fire Hazards
6.3 Static and Current Electricity
6.4 Occupational Safety, First Aid and Risk Management
6.5 Safety of Chemicals
6.6 Personnel Protective Equipments
6.7 Material Safety Data Sheet MSDS
6.8 Fundamentals and Regulations pertaining to Safety
6.9 Physical & Physiological Factors influencing safety
6.10 Engineering techniques for accident prevention
6.11 Emergency Management
6.12 Process Safety